**2.3 Alcohol consumption**

Several studies including meta-analysis, many cohort, and experimental studies, have reported the association between chronic intake of alcohol and increase in the risk of colon cancer [8, 9]. High or moderate intake of alcohol (> 12.5 grams/day) is associated with increased incidence of CRC and its mortality [10]. Although, there are discrepancies among various populations based on differences in genetic factors, body composition and other dietary factors including folate intake [8].
