**Abstract**

This chapter focuses on the importance of workers' personal resources during difficult times, such as the pandemic period. In particular, the role of self-compassion in the work context is examined as an important resource for maintaining psychophysical well-being. Further attention will be given to the impact of self-compassion on neuroscience research and possible organizational interventions to develop and/or support self-compassion in workers.

**Keywords:** self-compassion, COVID-19, occupational health, interventions, neuroscience
