**3.1 Factors that contribute to opioid misuse and examples of validated screening tools**

Given the need to balance the risks and benefits of use of opioids for chronic pain, how do we select who should receive an opioid prescription in any given clinical scenario? One key aspect of the answer lies in the determination of relative risk of misuse of the prescribed drug, which is dependent on multiple factors: drug factors, provider factors, and patient factors [34].
