**5. Conclusion**

As you know, the coronavirus epidemic has been affecting all countries financially and socially for almost two years, and like all other viral diseases, it will certainly not be eradicated soon, but it will threaten humanity in a new way each time. In the last

20 years, three CoVsubspecies transmitted to humans, and established researchers must continue to further develop identification and observation methods to prevent such adverse effects in the future.

Worldwide routine observation of SARS-CoV-2 variations and their consequences for destructiveness and right now utilized therapeutics will permit researchers to evaluate on the off chance that immunizations and different treatments are expected to be refreshed occasionally. New variations might infiltrate group invulnerability and taint unvaccinated people or work with immunization escape, which can incline these people toward extreme illness or passing. Nonetheless, most investigations have proposed that antibodies are as yet viable against the now coursing variations and can safeguard against extreme to direct illness results. Proof supporting the utilization of even a single vaccination dosage in keeping serious sickness from the Delta variation in the UK has featured the requirement for quicker immunization arrangement and rollout in more unfortunate areas like Africa. It is trusted that the in-house assembling of Covid-19 immunizations will help South Africa as well as the remainder of the African mainland to accomplish this objective. Also, more examinations are expected to assess the purpose for leading-edge diseases and the chance of winding down resistance to SARS-CoV-2 as well as the job that booster immunization dosages could play in counteraction. To lessen the risk of new and possibly more malicious variants from arising, health specialists ought in on vaccinating people as quickly as could be expected and ought to keep on underscoring the significance of maskwearing and social distancing. A multipronged treatment approach ought to keep on being carried out in nations, for example, South Africa has a high predominance of co-morbidities, for example, HIV, which might add to the rise of variations. This would not just save lives, yet additionally, give restricted space for the viral to develop. While it may not be imaginable to foresee what the following VOC will be, we can gain from previous encounters and difficulties to more likely adapt to the situation at hand. SARS-CoV-2 is not supposed to vanish soon, however, will probably turn into a (the) essential medical care issue from now on, and as such will stay a challenge.

Besides, the amount of information on the connections between lung cancer and Covid-19 contamination has become richer, mainly because of studies on several patients in multicenter. It is, in this way, vital to make a protected medical care framework during the Covid-19 pandemic and it is fundamental to support clinical service conveyance to patients with lung cancer. One of the hypotheses about the SARS-CoV-2 virus is that it can change the mechanism of its entry into the host cell, that is, the binding to the host receptor no longer occurs through the spike protein and occurs by another method, and, in that method, new mutations occur that make it harder for researchers to find a treatment for this disease, like many other diseases, will be inexhaustible and will constantly evolving.

*SARS-CoV-2 Mutation Mechanism, Features, and Future Perspective DOI: http://dx.doi.org/10.5772/intechopen.106905*
