**5.2 Genetic information**

The human genome contains around 3 billion base matches, equivalent to roughly 1.5 GB of material. A few inherited illnesses are unprecedented, while others, like hypertension, diabetes, and Alzheimer's infection, have been connected to a

hereditary weakness. Researchers can gain a superior handle of the cycles hidden a large number of these uncommon infections and normal clinical problems by utilizing genomic planning.

The planning information can then be utilized to plan pertinent arrangements and drives. Researchers should gather however much data on sicknesses as could reasonably be expected from people who are impacted by them. Unfortunate information access and interoperability has forever been and keeps on being a worry in medical care. Over 10 years after the human genome project was done, specialized upgrades have made having one's genome sequenced and hereditary data examined extensively more reasonable.

Ten years prior, the expense of genome sequencing would have been \$10,000,000. Today, the expense has been altogether diminished to around \$1000. This implies how much hereditary information will keep on developing when genome sequencing is economical.

Frequently, hereditary information might not have an obviously perceived proprietor, making it powerless against unpredictable dispersal and raising protection worries for the genuine proprietor. In the absence of viable strategies for security and validation, the gigantic number of accessible hereditary information raises serious difficulties that can be settled by the progressive blockchain innovation.

Blockchain is an openly available report of digitalized exchanges and information put away in blocks. Blockchain lays out a decentralized organization of distributable information that might be traded among interconnected data set frameworks. Blockchain innovation utilizes a timestamped permanent arrangement of information obstructs that are accessible to anyone with a connected framework, anyplace on the planet, for however long they are appropriately approved.

This innovation permits buyers decision over how their information is conveyed, protecting their security. Clients can encode their information utilizing unbalanced encryption (Public Key Cryptography) for expanded security. However, when selling or donating data, the receiver is given a private key to decrypt the data, guaranteeing that no unauthorized third party gets access.

Blockchain enables direct connection between data sources (users) and purchasers (pharma companies, research institutes). Furthermore, cryptographic keys protect users' anonymity throughout data sharing.

These purchasers may then use the data sets to research genetic trends in a certain population, allowing for the creation of medications and other therapies depending on the genetic profiles assessed. Blockchain decreases the danger of data change and manipulation by using cryptographic blocks, offering a genuine database for research and the development of novel diagnoses and treatment options for uncommon conditions.

When DNA sequencing data is added to a blockchain database, it generates a block with a timestamp. To avoid data manipulation, each block is cryptographically connected to the other blocks in the chain. Furthermore, with smart contracts, blockchain technology offers data owners control over what information is shared and with whom it is shared.
