**Abstract**

This paper gives a thorough evaluation of the literature on blockchain applications in healthcare. The evaluation included 42 papers that presented current information on the existing implications and gaps in the usage of blockchain technology for enhancing healthcare systems. According to the SLR results, blockchain is being utilized to produce unique and sophisticated solutions to enhance the prevailing standards of medical data handling, sharing, and processing. In the healthcare business, blockchain technology is experiencing conceptual evolution, adding considerable value through enhanced efficiency, access control, technical innovation, privacy protection, and data management process security. The findings also indicate that the current limits are mostly related to model performance, as well as the constraints and costs involved with implementation. An integrated approach is offered to cover prospective areas where future researchers might bring considerable value, such as regulatory compliance, system architecture, and data protection. Finally, the SLR believes that further research can help to enable the wider implementation of blockchain applications to handle crucial challenges like as medical diagnostics, legal compliance, preventing fraud, and enhancing patient care in remote monitoring or medical emergencies.

**Keywords:** healthcare, biomedical, data sharing, medicine, distributed ledger technology, distributed systems, health information exchange, security, interoperability, transparency, privacy
