**7.3 Allergenicity**

Another main issue associated with edible insects is allergy. Anaphylactic reactions have been found in several studies after eating edible insects; these reactions may have been triggered by the existing link between insects and arthropods (such as shrimps and dust mites). Purines are made up of hydrogen, carbon, and nitrogen, as well as adenine and guanine, and are found in proteins. Uric acid is just another product of purine metabolism in humans that can be hazardous to gout sufferers. Undeniably cross allergic reactions to crustaceans and house dust mite protein have been associated with various insects. Co sensitivity and cross-reactivity between crustaceans, house dust mite, and edible insects have been studied and it was found that tropomyosin and arginine kinase are the major proteins responsible for allergic reactions [77]. Broekman *et al.* studied allergic reactions corresponding to insect consumption [78]. Different methods such as enzymatic hydrolysis and thermal treatment have been used to reduce the intensity of various allergens in various studies that are somehow effective [21].
