**1. Introduction**

The increasing complexity of the phenomenon of resistance of enterobacteria against beta-lactamines in Cameroon will be a major public health problem if

nothing is done. The study of the enzymatic systems involved in inducing these resistances in the cities of Yaoundé, Ngaoundéré and Douala has shown evolutions in space and time [1–3]. In the city of Maroua, the alarm was raised with the identification of multi-resistant microorganisms in dairy products and raw meat sold in the city [4, 5]. These resistances have been attributed to the production of high-level cephalosporinases and b-lactamases including Carbapenemases [5, 6]. The concern in relation to these observations is that, microorganisms with similar profiles have started to be isolated from biological samples at the National Social Insurance Fund (MSC-NSIF) of Maroua. Moreover, cases of death were noted due to infections by this category of Enterobacteriaceae before the end of the analysis of the samples, although routine antibiotics were administered (MSC-NSIF patient files). The emergence of carbapenemase-producing Enterobacteriaceae (EPC) in the city of Maroua could in the future, become the main factor of therapeutic failures. In a socio-economic context where probably antibiotic therapy remains the most widely used strategy, knowledge of the enzyme systems involved in these enterobacteria could make patient management more effective. The objective of this study is to determine the types of carbapenemases moving around in the city of Maroua with a view to developing a strategy control to fight against the enterobacteria that produce them.
