**4. Conclusion**

The objective of this work was to determine the types of carbapenemases moving around the city of Maroua in order to contribute to the development of a control strategy against the enterobacteria multidrug resistance. It was found that *Arizona, C. braakii, E. asburiae, E. gergoviae, P. mirabilis, P. vulgaris, S. ficaria* and *S. odorifera* 1 are the species of enterobacteria that produce carbapenemases in biological samples (urine, wound pus, osteitis pus, blood, stools). The carbapenemases identified are of the KPC, OXA and undetermined types. 11 different substrates and inhibition profiles are expressed by these microorganisms, some of which are able to produce two different classes of carbapenemases, others of producing a carbapenemase-BLSE or cephalosporinase combination. These 11 profiles have shown the difficulties of applying law of inhibition of these carbapenemases in situ in the context of probabilistic antibiotic therapy. This observation is valid whether the enterobacterium is identified or the biological medium of isolation is known.
