**Abstract**

Persistent cases of *Salmonella* infection have urged great attention and surveillance on this foodborne pathogen. *Salmonella* continues to be a significant foodborne disease worldwide for both animals and people in the twenty-first century. It is one of the leading causes of foodborne pathogens infecting animals and humans. Salmonellosis is a principal cause of food poisoning and is, hence, a severe public health problem. The history, classification and nomenclature of *Salmonella*, as well as its characteristics, clinical manifestations, epidemiology and route of contamination, will be covered in this chapter to help readers gain a better understanding and overview of this microbe.

**Keywords:** *Salmonella*, foodborne, pathogens, food poisoning
