*5.1.3 Fosfomycin*

It is also a bactericidal drug that blocks cell wall synthesis at early stages. It's a widely used drug as a single dose of 3 g is used for the treatment of uncomplicated UTI, and also because of its activity against ESBL and MBL (metallo-β-lactamases). Resistance to fosfomycin is not widespread till date, however, if present may be conferred by:

