**Abstract**

Soybean is the main commodity of Brazilian agribusiness, and the country stands out for the largest world production of this oilseed. The culture is carried out under two main forms of cultivation, conventional and in the form of no tillage. The possibility of two to three agricultural crops per year contributes to the emergence of various plant protection problems, including soybean rust, the stinkbug complex, defoliating caterpillars, nematodes, in addition to competition with weeds. Thus, the purpose of this chapter is to describe the main application techniques of chemical or biological products in the control of agents that are harmful to the soybean crop, as well as to bring technological innovations involving remote sensing, unmanned aerial vehicle, and other techniques of application in the control of these harmful agents to the crop. Also comment on the benefits of spray adjuvants and the limitations of tank-mixes with plant protection products intended for soybean cultivation.

**Keywords:** pesticide application methods, remote sensing, unmanned aerial vehicle, chemical and biological control, *Glycine max*
