**5. Conclusions**

Ginger contains diverse bioactive compounds and demonstrates multiple bioactive properties. It is a potent antioxidant, anti-inflammatory, regulator of lipid profile, inhibitor of VSMC proliferation, blocker of voltage-dependent Ca2+ channels, inhibitor of platelet aggregation, regulator of endothelial dysfunction and NO synthesis, enhancer of cholesterol efflux from macrophages, inhibitor of angiogenesis, and promoter of autophagy.

The biological activities, health benefits, and cardioprotective properties of ginger/ginger constituents along with related mechanisms of action gave new insights to show new avenues in the treatment of CVDs.

It is valuable to explore new anti-platelet aggregation drugs based on the skeleton of [*n*]-paradol or other principles reported from the *Zingiber* series.
