*Metabolomics and Genetic Engineering for Secondary Metabolites Discovery DOI: http://dx.doi.org/10.5772/intechopen.102838*

applications. The integration between genetic engineering and metabolomic provides a powerful platform for the production, detection, and characterization of known and unknown secondary metabolites. However, the combination between CRISPR-Cas9 and metabolomics may improve the efficiency of microbial SMs discovery. Thus, the need of the hour is a comprehensive and sensitive technique that has the ability to provide comprehensive information of any secondary metabolites under all conditions.
