*Methodological Quality of Clinical Practice Guidelines for Pharmacological Prophylaxis… DOI: http://dx.doi.org/10.5772/intechopen.103660*

Guideline Development; 09. International Union Angiology (IUA, 2013): Prevention and Treatment of Venous Thromboembolism; 10. Medication Services (Queensland Health, 2018): Guideline for the Prevention of Venous Thromboembolism (VTE) in Adult Hospitalized Patients; 11. Colégio Mexicano de Ortopedia y Traumatología (Mexicano, 2011): Declaración de posición conjunta del Colegio Mexicano de Ortopedia y Traumatología: Profilaxis de la enfermedad tromboembólica venosa en cirugía ortopédica de alto riesgo; 12. Ministry of Health of Malaysia (MOH, 2013): Clinical Practice Guidelines: Prevention and Treatment of Venous Thromboembolism; 13. Researchers Group (Argentina, 2013): Guía de recomendaciones para la profilaxis de la enfermedad tromboembólica venosa en adultos en la Argentina; 14. Japanese Circulation Society (JCS, 2011): Guidelines for the Diagnosis, Treatment, and Prevention of Pulmonary Thromboembolism and Deep Vein Thrombosis;

The methodological quality of fourteen (14) CPGs was assessed by AGREE II instrument. Seven (50%) guidelines obtained scores equal to or greater than 60% in domains 3 or 6 being considered of high quality as described in **Table 6**. The mean scores for the domains were: scope and purpose 72%, stakeholder involvement 56%, rigor of development 56%, clarity of presentation 70%, applicability 41%, and editorial Independence 55%.


#### **Table 6.**

*Clinical practice guidelines for pharmacological prophylaxis of VTE in hospitalized adult medical and surgical patients with high quality assessed by AGREE II.*
