**3.2 Methodological quality of clinical practice guidelines**

The AGREE II standardized domain ratings are summarized in **Table 5**.

*Methodological Quality of Clinical Practice Guidelines for Pharmacological Prophylaxis… DOI: http://dx.doi.org/10.5772/intechopen.103660*

**Figure 2.** *PRISMA flow diagram of study selection.*

01. National Institute for Health and Care Excellence (NICE, 2018): Venous thromboembolism in over 16 s Reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism; 02. American Society of Hematology (ASH, 2018): American Society of Hematology guidelines for the management of venous thromboembolism: Prevention of venous thromboembolism in surgical and medical hospitalized patients; 03. Scottish Intercollegiate Guidelines Network (SIGN, 2014): Prevention and management of venous thromboembolism; 04. German interdisciplinary, evidence- and consensus-based (S3, 2015): Clinical practice guideline: The prophylaxis of venous thromboembolism; 05. National Health and Medical Research Council (NHMRC, 2012): Clinical practice guideline for the prevention of venous thromboembolism in patients admitted to Australian hospitals; 06. American College of Chest Physicians (ACCP, 2012): Antithrombotic Therapy and Prevention of Thrombosis, 9th ed.: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines; 07. American College Physicians (ACP, 2011): Venous thromboembolism prophylaxis in hospitalized patients: A clinical practice guideline from the American College of Physicians; 08. Saudi Scientific Hematology Society and the Saudi Association for VTE (SAVTE, 2013): Saudi Arabian Handbook for Healthcare


*Anticoagulation - Current Perspectives*

**Table 5.**

*AGREE II standardized domain scores for the 14 included CPGs for pharmacological prophylaxis of VTE in hospitalized adult*

 *surgical and medical patients.*
