**Table 1.**

*Several smart polymeric drug delivery technologies are available [7].*

*Selection and Role of Polymers for Designing of a Drug Carrier DOI: http://dx.doi.org/10.5772/intechopen.103125*

The reactive oxygen system, the result of aerobic metabolism, is what activates oxidation reactive systems. Oxidation reactive materials include sulfur-based compounds. To accomplish the lipophilic-hydrophilic shift, reactive oxygen moiety can oxidize poly(propylene sulfide) (PPS) to generate sulphoxide [63]. The comparatively higher stability of sulfur in sulfur-containing substances is a fundamental restriction, and the reaction to reactive oxygen may not be as sensitive. The addition of selenium to the polymeric materials, which will be more sensitive than sulfur, improves the susceptibility of the reaction to reactive oxygen [64]. Owing to its own oxidation responsiveness, ferrocene-containing polymeric materials are another prominent family of oxidation reactive polymers [65, 66]. Ferrocene can be inserted in the framework, side chain, and terminal unit of the polymeric materials. Developing themes such as boronic ester moieties, oligoproline, and tetrathiafulvalene have been studied for the development of new oxidation-sensitive polymeric substances to broaden the uses [67, 68].
