**3.4 Comparative analysis for the selection of nanocapsules production method**

**Table 1** summarizes the main advantages and disadvantages of the processing methods described in Section 3 in terms of water volume consumption, additional purification steps, contaminant generation, time consumption, and others. Overall, nanoprecipitation represents a simple, fast, low-cost, and versatile method, but its simplicity can lead to some repeatability and scale-up problems. In contrast, emulsion template methods need agitation and solvent removal equipment and thus the technique becomes more expensive but with better control of particle size and scale response. Finally, the LBL technique offers many possibilities, as several active ingredients of different nature can be encapsulated simultaneously, and the release mechanism can be controlled according to the nature and number of polyelectrolyte layers; however, it becomes a more complex and time-consuming technique and larger particle sizes can be obtained compared to the other methods. The selection of the nanocapsule production method should mainly consider the desired characteristics of the final nanocarrier, the formulation materials, and the availability of laboratory equipment [5].

*Lipid and Polymeric Nanocapsules DOI: http://dx.doi.org/10.5772/intechopen.103906*


**Table 1.**

*Comparative analysis of the advantages and disadvantages of nanocapsule production methods.*
