**5. Conclusions**

Nano lipid structure carriers, composition and formulations techniques have a profound influence on their physicochemical properties and efficacy as drug delivery systems. The lipid carriers have evolved over the years and they have shown promise for treating various clinical diseases and complications including psoriasis, dermatitis, rosacea, vitiligo, acne, fungal infections, several systemic infections, etc. Taking into account the increase in the number of patented NLCs-based formulations and the increase in the availability of data so far, it can be expected that the number of clinical trials pertaining NLCs will substantially increase in near future. Moreover, now NLCs appear to be one step closer to its translation into the market to the clinic.
