**4.2 Gold nanoparticles**

Gold nanoparticles (AuNPs) can also be loaded on various plant gum drug carriers and be used as antibacterial agents. Gold nanoparticles (AuNPs) have exceptional stability against oxidation and therefore may play a significant role in the advancement of clinically useful diagnostic and therapeutic Nanomedicines. That being said, conventional process for synthesis of these metallic nanoparticles utilizes toxic reagents as reducing agents, additional capping agents for stability as well as surface functionalization for drug delivery purposes.

Just like silver NPs, *P. domestica* gum can also be loaded with AuNPs. Preparation and assessment in this study were performed like *P. domestica* gum-loaded silver NPs and the antibacterial effect was studied on Gram-positive (*S. aureus*), Gram-negative (*E. coli* and *P. aeruginosa*) bacteria.

Kondagogu gum is also one of the drug carriers that was used in a study for AuNPs in order to demonstrate their effects on *E. coli* and *Bacillus subtilis*. After the preparation of these NPs, their concentration, and reaction time on the synthesis of AuNPs were investigated by using techniques like UV-visible spectroscopy, FTIR, and XRD.
