*4.3.8 Antifungal effect*

The fungicidal properties of acetone extracts reveal the potential of *D. stramonium* seeds as a natural source of antifungal agent, according to Mdee et al. [78]. DS extracts have MICs ranging from 1.25 to 2.50 mg/mL.

#### *4.3.9 Insecticidal effect*

The odor of the Datura plant functions as a repellant for a variety of insects and pests. Under laboratory conditions, Kurnal et al. [79] found that ethanol extracts of *D. stramonium* leaf and seed have substantial acaricidal, repellant, and oviposition deterrent effect against adult two-spotted spider mites (Tetranychusurticae). After 48 hours, leaf and seed extracts at concentrations of 167.25 and 145.75 g/L (applied using a Petri leaf disc-spray tower method) killed 98 percent and 25 percent of spider mite adults, respectively. These findings imply that *D. stramonium* may be useful in the treatment of two-spotted spider mites.

#### *4.3.10 Dosage*

*D. stramonium* is generally administrated at a dose of 60–185 mg powder for leaf and 60–120 mg powder for seed [80].
