**1. Introduction**

*Calotropis procera (Aiton)* Dryand has a powerful insecticidal, antimalarial, antiviral, antimicrobial, analgesic, antifertility, antitumor, antihyperglycemic, hepatoprotective, anti-inflammatory, antidiarrhoeal, anticonvulsant, oestrogenic, antidiabetic and anthelmintic activity. Actually where ever observe, the plant is available on road sides

[1]. *C. procera* is a flowering plant and it belongs to *Asclepiadaceae* family. The *C. procera* is native to Africa, Arabian Peninsula, Western Asia, the Indian Subcontinent and Indo-China. The plant is a most powerful latex plant, and it attracts insects. In this plant plenty of medicinally useful secondary metabolites are present, those are cardenolides, terpenoids and anthocyanins, for this reason, collected fresh fruit and coarse powder for detailed anatomy of T.S, L.S RLS, LRS, powder microscopy, Extractive, Fluorescence and Preliminary Phytochemical studies. Therefore, present work was carried out to study the Pharmacognostical studies on the fruit of *Calotropis procera* (Aiton) Dryand.
