**5.3 Anti-diabetic**

Diabetes mellitus is characterized by high glucose levels (Blood sugar) which is a type of metabolic disorder. Insulin secretion, or insulin action or both can be defective in response to the high blood sugar (glucose) levels in this disease. Type 2 diabetes have two features- low gradic chronic inflammatory and the insulin resistance. Cardiovascular diseases and many other multi organ disorders can be developed by type 2 diabetes. Leaves of *M. alba* helps to decrease the blood glucose level and also prevents potential histo-pathological alterations in pancreas and kidneys which is observed in brown rats, in a recent experiment [14]. Soluble extract of *M. alba* fruit found effective in decreasing fasting blood glucose (FBG) and glycosylated serum protein (GSP) in STZ induced diabetic mice. In STZ induced diabetic rats *M. alba* stem bark also helps in the alternation of glutathione and insulin levels [2, 16, 40].


*Mulberry as a Valuable Resource for Food and Pharmaceutical Industries: A Review DOI: http://dx.doi.org/10.5772/intechopen.104631*


#### **Table 2.**

*Pharmaceutical importance of mulberry.*
