**6.7 Antifertility activity**

Protective effect of ethanolic extract of *A. aspera* against fertility is now being investigated including antizygotic activity, blastocytotoxic activity and abortifacient activity. The results showed the extract of *A. aspera* having antifertility and antiestrogenic effect in female rats. Administration of ethanolic extract of *A. aspera* to the animals at a dose of 200 mg/kg and 400 mg/kg significantly decrease in the duration of estrous & metesterous phase. Treated the animals with ethanolic extract of it at a dose of 200 and 400 mg/kg reduced the weight of ovaries than the control group [18].
