**Abstract**

*Calotropis procera* (Aiton) Dryand (Asclepiadaceae) is very well-known latex wild plant, it is covered in tropical Asia and Africa, traditionally as well as medicinally the plant has been used for insecticidal, antimalarial, antiviral, antimicrobial, analgesic, antifertility, antitumor, antihyperglycemic, hepatoprotective, anti-inflammatory, antidiarrhoeal, anticonvulsant, oestrogenic, antidiabetic and anthelmintic activity. For this reason, the main theme of research work was carried out on detailed pharmacognistical studies for quality control and standardization and this study provides the basis for the herbal remedy and provide physiological information about plant species. This research is helpful to identify and estimate the purity of the drug and can also be used to screen for adulteration and gives a drug quality. This comprehensive research work is for identification, collection, authentication and it is easy to identify the adulterants. Detailed macroscopical, T.S, L.S, Powder microscopy, Physicochemical parameters, Extractive values, Fluorescence, Preliminary Phytochemical studies were performed as per the standard. It is a very important research work and the author had has been established the evaluation standards for a medicinal plant. This evaluation is for the authentication of a fruit plant of *Calotropis procera* and the fruit physiology is useful for both qualitative and quantitative estimation of the medicinal herbal drugs.

**Keywords:** *Calotropis procera* fruit, pharmacognostical standardization, quality control
