**Abstract**

Plants that possess therapeutic characteristics have been used in medicine from the beginning of time. Indigenous medicine has been practiced as a preventative approach in tropical areas to combat general infections, including viral infections. The family of Annonaceae species of plants, broadly distributed in these areas, is dedicated to one such plant-based medication. *Annona muricata* realistically is among the most well-known of these. A novel coronavirus (2019-nCoV) was typically identified as the reliable source of a viral pneumonia outbreak in January 2020 in Wuhan, China. Traditional medicine is reasonably believed to represent a possible opportunity in the successful fight against COVID-19. The Cameroonian response strategy has been properly implemented in outstanding community services without much practical efficiency on transmission rates. The reason for this is that people did not follow the government's prescriptions. As a direct result, local people would knowingly employ self-prescribed herbal medications to aggressively combat the COVID-19 spread. Local health officials should take action and recognize the value of species diversity mostly in the fight against the COVID 19 pandemic, making it available to the concerned public with the support of scientific and ethno pharmacological local institutions. The potential therapeutic usage of *Annona muricata* as an antiviral agent to powerfully aid in the possible fight against COVID 19 has been carefully investigated in this paper.

**Keywords:** *Annona muricata*, soursop fruit, health benefits, traditional uses, COVID 19
