*4.3.7 Antimicrobial effect*

The bactericidal activity of methanol extracts of the aerial portion of DS against gram-positive bacteria was dosage dependent [48]. Sharma et al. [77] claimed that DS was highly efficient as a vibriocidal against Vibreo cholerae and Vibreo parahaemolyticus strains. The MIC value of acetone extracts of DS was in the range of 2.5–15 mg/mL, making them effective as broad spectrum vibriocidal agents.
