**7.3 Selective 5-hydroxytryptamine reuptake inhibitors**

These drugs also called as selective serotonin reuptake inhibitors or SSRIs, including flouxetine, fluvoxamine, paroxetine, citalopram and sertraline. SSRIs are most commonly prescribed for the treatment of depression. These are showing selectivity for the 5-HT not for noradrenaline uptake. SSRIs produced less anticholinergic side effects than the tricyclic antidepressant drugs. They are equally effective as MAOIs and TCAs for treating the depression but in case of severe depression, less effective than TCAs [76].
