**10. Conclusions**

HS is a chronic disease that causes significant weakness and suffering. Its onset in young adulthood leads to loss of productivity given the limiting nature of the disease. Treatment must be individualized, according to the extent, severity, and degree of interference in quality of life. Topical or oral antibiotic therapy may be effective to treat mild diseases in small areas. Biological agents can be applied to severe or widespread diseases. New treatment options are emerging to target inflammatory agents. Perianal, perineal, and refractory cases of HS should be vigorously treated. Best outcomes are achieved with large resections and reconstructive procedures.
