**7. Conclusion**

Drugs are a common cause of chronic diarrhea and enteropathy by a number of mechanisms including intrinsic mode of action, malabsorption, dysbiosis, increased GI motility, alterations in water and electrolyte absorption and secretion mechanisms, autoimmune macroscopic or microscopic damage, and cytotoxic effect. Site of damage may include either part of the small intestine, colon, or both, and can be manifested by malabsorptive, inflammatory or watery diarrhea. In most cases diarrhea subsides after drug withdrawal, but in some cases a number of inflammatory conditions requiring other forms of therapy may be needed.

*Benign Anorectal Disorders - An Update*
