*2.6.1.1 Butyric acid (BA)*

BA represents one of the most potent SCFAs, acting both in intestinal and parenteral way [91].

The complex intestinal effects of BA are the following [92–95]:


*Efficiency of Treatment Targeted on Gut Microbiota in Inflammatory Bowel Diseases… DOI: http://dx.doi.org/10.5772/intechopen.108664*


At the moment, there are inconclusive results of the clinical studies using either rectal infusions or oral formulas with BA in patients with IBD.

The parenteral effect of BA, produced also though the inhibition of HDAC, consists of [96–98]:

