**Acknowledgements**

This chapter was supported by the Executive Unit for the Financing of Higher Education, Research, Development and Innovation (UEFISCDI) of the Ministry of National Education (project "PREdictive Machine Learning Algorithm for the Dynamic Evaluation of Pancreatic Cancer during Therapy Multimodal Therapy"— PREDYCT, code PN-III-P4-ID-PCE2020-0884 within PNCDI III).
