*Colorectal Anastomosis: The Critical Aspect of Any Colorectal Surgery DOI: http://dx.doi.org/10.5772/intechopen.107952*

[98] Petrucciani N, Sirimarco D, Nigri GR, et al. Robotic right colectomy: A worthwhile procedure? Results of a meta-analysis of trials comparing robotic versus laparoscopic right colectomy. Journal of Minimal Access Surgery. 2015;**11**:22-28

[99] Rink AD, Kienle P, Aigner F, Ulrich A. How to reduce anastomotic leakage in colorectal surgery-report from German expert meeting. Langenbeck's Archives of Surgery. 2020;**405**:223-232

[100] Li Z, Zhou Y, Tian G, et al. Metaanalysis on the efficacy of indocyanine green fluorescence angiography for reduction of anastomotic leakage after rectal cancer surgery. The American Surgeon. 2021;**87**:1910-1919

[101] Liu D, Liang L, Liu L, Zhu Z. Does intraoperative indocyanine green fluorescence angiography decrease the incidence of anastomotic leakage in colorectal surgery? A systematic review and meta-analysis. International Journal of Colorectal Disease. 2021;**36**:57-66

[102] Slesser AA, Pellino G, Shariq O, et al. Compression versus hand-sewn and stapled anastomosis in colorectal surgery: A systematic review and meta-analysis of randomized controlled trials. Techniques in Coloproctology. 2016;**20**:667-676

[103] Martinez-Perez A, Carra MC, Brunetti F, de'Angelis N. Short-term clinical outcomes of laparoscopic vs open rectal excision for rectal cancer: A systematic review and meta-analysis. World Journal of Gastroenterology. 2017;**23**:7906-7916

[104] Puleo S, Sofia M, Trovato MA, et al. Ileocolonic anastomosis: Preferred techniques in 999 patients. A multicentric study. Surgery Today. 2013;**43**:1145-1149

[105] Choy PY, Bissett IP, Docherty JG, et al. Stapled versus handsewn methods for ileocolic anastomoses. Cochrane Database of Systematic Reviews. 2011;**9**:CD004320

[106] Balciscueta Z, Uribe N, Caubet L, et al. Impact of the number of stapler firings on anastomotic leakage in laparoscopic rectal surgery: A systematic review and meta-analysis. Techniques in Coloproctology. 2020;**24**:919-925

[107] Braunschmid T, Hartig N, Baumann L, et al. Influence of multiple stapler firings used for rectal division on colorectal anastomotic leak rate. Surgical Endoscopy. 2017;**31**:5318-5326

[108] Otsuka K, Kimura T, Matsuo T, et al. Laparoscopic low anterior resection with two planned stapler fires. Journal of the Society of Laparoendoscopic Surgeons. 2019;**23**. ISSN: 1938-3797(Electronic), 1086-8089(Linking). DOI :10.4293/ JSLS.2018.00112

[109] Pla-Marti V, Martin-Arevalo J, Moro-Valdezate D, et al. Impact of the novel powered circular stapler on risk of anastomotic leakage in colorectal anastomosis: A propensity score-matched study. Techniques in Coloproctology. 2021;**25**:279-284

[110] Chen J, Zhang Y, Jiang C, et al. Temporary ileostomy versus colostomy for colorectal anastomosis: Evidence from 12 studies. Scandinavian Journal of Gastroenterology. 2013;**48**:556-562

[111] Rondelli F, Reboldi P, Rulli A, et al. Loop ileostomy versus loop colostomy for fecal diversion after colorectal or coloanal anastomosis: A meta-analysis. International Journal of Colorectal Disease. 2009;**24**:479-488

[112] Matthiessen P, Hallbook O, Andersson M, et al. Risk factors for anastomotic leakage after anterior resection of the rectum. Colorectal Disease. 2004;**6**:462-469

[113] Chude GG, Rayate NV, Patris V, et al. Defunctioning loop ileostomy with low anterior resection for distal rectal cancer: Should we make an ileostomy as a routine procedure? A prospective randomized study. Hepatogastroenterology. 2008;**55**:1562-1567

[114] Martinou E, Drakopoulou S, Aravidou E, et al. Parecoxib's effects on anastomotic and abdominal wound healing: A randomized controlled trial. The Journal of Surgical Research. 2018;**223**:165-173

[115] Burton TP, Mittal A, Soop M. Nonsteroidal anti-inflammatory drugs and anastomotic dehiscence in bowel surgery: Systematic review and metaanalysis of randomized, controlled trials. Diseases of the Colon and Rectum. 2013;**56**:126-134

[116] Chen W, Liu J, Yang Y, et al. Ketorolac administration after colorectal surgery increases anastomotic leak rate: A meta-analysis and systematic review. Frontiers in Surgery. 2022;**9**:652806

[117] Gorissen KJ, Benning D, Berghmans T, et al. Risk of anastomotic leakage with non-steroidal antiinflammatory drugs in colorectal surgery. The British Journal of Surgery. 2012;**99**:721-727

[118] Holte K, Andersen J, Jakobsen DH, Kehlet H. Cyclo-oxygenase 2 inhibitors and the risk of anastomotic leakage after fast-track colonic surgery. The British Journal of Surgery. 2009;**96**:650-654

[119] Klein M, Krarup PM, Kongsbak MB, et al. Effect of postoperative diclofenac on anastomotic healing, skin wounds and subcutaneous collagen accumulation:

A randomized, blinded, placebocontrolled, experimental study. European Surgical Research. 2012;**48**:73-78

[120] Gustafsson UO, Scott MJ, Hubner M, et al. Guidelines for perioperative care in elective colorectal surgery: Enhanced recovery after surgery (ERAS((R))) society recommendations: 2018. World Journal of Surgery. 2019;**43**:659-695

[121] Peng F, Liu S, Hu Y, et al. Influence of perioperative nonsteroidal antiinflammatory drugs on complications after gastrointestinal surgery: A meta-analysis. Acta Anaesthesiologica Taiwanica. 2016;**54**:121-128

[122] Chiarello MM, Fransvea P, Cariati M, et al. Anastomotic leakage in colorectal cancer surgery. Surgical Oncology. 2022;**40**:101708

[123] Garcia-Granero A, Frasson M, Flor-Lorente B, et al. Procalcitonin and C-reactive protein as early predictors of anastomotic leak in colorectal surgery: A prospective observational study. Diseases of the Colon and Rectum. 2013;**56**:475-483

[124] Marres CCM, van de Ven AWH, Leijssen LGJ, et al. Colorectal anastomotic leak: Delay in reintervention after false-negative computed tomography scan is a reason for concern. Techniques in Coloproctology. 2017;**21**:709-714

[125] Bostrom P, Svensson J, Brorsson C, Rutegard M. Early postoperative pain as a marker of anastomotic leakage in colorectal cancer surgery. International Journal of Colorectal Disease. 2021;**36**:1955-1963

[126] den Dulk M, Witvliet MJ, Kortram K, et al. The DULK (Dutch leakage) and modified DULK score

*Colorectal Anastomosis: The Critical Aspect of Any Colorectal Surgery DOI: http://dx.doi.org/10.5772/intechopen.107952*

compared: Actively seek the leak. Colorectal Disease. 2013;**15**:e528-e533

[127] Luo J, Wu H, Jiang Y, et al. The role of heart rate, body temperature, and respiratory rate in predicting anastomotic leakage following surgery for rectal cancer. Mediators of Inflammation. 2021;**2021**:8698923

[128] Stearns AT, Liccardo F, Tan KN, et al. Physiological changes after colorectal surgery suggest that anastomotic leakage is an early event: A retrospective cohort study. Colorectal Disease. 2019;**21**:297-306

[129] den Dulk M, Noter SL, Hendriks ER, et al. Improved diagnosis and treatment of anastomotic leakage after colorectal surgery. European Journal of Surgical Oncology. 2009;**35**:420-426

[130] Warschkow R, Steffen T, Beutner U, et al. Diagnostic accuracy of C-reactive protein and white blood cell counts in the early detection of inflammatory complications after open resection of colorectal cancer: A retrospective study of 1,187 patients. International Journal of Colorectal Disease. 2012;**27**:1377

[131] Shaaban H, Daniel S, Sison R, et al. Eosinopenia: Is it a good marker of sepsis in comparison to procalcitonin and C-reactive protein levels for patients admitted to a critical care unit in an urban hospital? Journal of Critical Care. 2010;**25**:570-575

[132] Davido B, Makhloufi S, Matt M, et al. Changes in eosinophil count during bacterial infection: Revisiting an old marker to assess the efficacy of antimicrobial therapy. International Journal of Infectious Diseases. 2017;**61**:62-66

[133] Lin Y, Rong J, Zhang Z. Silent existence of eosinopenia in sepsis:

A systematic review and meta-analysis. BMC Infectious Diseases. 2021;**21**:471

[134] Su'a BU, Mikaere HL, Rahiri JL, et al. Systematic review of the role of biomarkers in diagnosing anastomotic leakage following colorectal surgery. The British Journal of Surgery. 2017;**104**:503-512

[135] Vijayan AL, Vanimaya RS, et al. Procalcitonin: A promising diagnostic marker for sepsis and antibiotic therapy. Journal of Intensive Care. 2017;**5**:51

[136] Facy O, Paquette B, Orry D, et al. Diagnostic accuracy of inflammatory markers as early predictors of infection after elective colorectal surgery: Results from the IMACORS study. Annals of Surgery. 2016;**263**:961-966

[137] Giaccaglia V, Salvi PF, Antonelli MS, et al. Procalcitonin reveals early dehiscence in colorectal surgery: The PREDICS study. Annals of Surgery. 2016;**263**:967-972

[138] Shimura T, Toiyama Y, Hiro J, et al. Monitoring perioperative serum albumin can identify anastomotic leakage in colorectal cancer patients with curative intent. Asian Journal of Surgery. 2018;**41**:30-38

[139] Ge X, Cao Y, Wang H, et al. Diagnostic accuracy of the postoperative ratio of C-reactive protein to albumin for complications after colorectal surgery. World Journal of Surgical Oncology. 2017;**15**:15

[140] Komen N, Slieker J, Willemsen P, et al. Polymerase chain reaction for *Enterococcus faecalis* in drain fluid: The first screening test for symptomatic colorectal anastomotic leakage. The appeal-study: Analysis of parameters predictive for evident anastomotic leakage. International Journal of Colorectal Disease. 2014;**29**:15-21

[141] Rojas-Machado SA, Romero M, Arroyo A, et al. Anastomic leak in colorectal cancer surgery. Development of a diagnostic index (DIACOLE). International Journal of Surgery. 2016;**27**:92-98

[142] Adams K, Papagrigoriadis S. Creation of an effective colorectal anastomotic leak early detection tool using an artificial neural network. International Journal of Colorectal Disease. 2014;**29**:437-443

[143] Tang CL, Seow-Choen F. Digital rectal examination compares favourably with conventional water-soluble contrast enema in the assessment of anastomotic healing after low rectal excision: A cohort study. International Journal of Colorectal Disease. 2005;**20**:262-266

[144] Habib K, Gupta A, White D, et al. Utility of contrast enema to assess anastomotic integrity and the natural history of radiological leaks after low rectal surgery: Systematic review and meta-analysis. International Journal of Colorectal Disease. 2015;**30**:1007-1014

[145] Hirst NA, Tiernan JP, Millner PA, Jayne DG. Systematic review of methods to predict and detect anastomotic leakage in colorectal surgery. Colorectal Disease. 2014;**16**:95-109

[146] Fransvea P, Costa G, D'Agostino L, et al. Redo-laparoscopy in the management of complications after laparoscopic colorectal surgery: A systematic review and meta-analysis of surgical outcomes. Techniques in Coloproctology. 2021;**25**:371-383

[147] Rotholtz NA, Angeramo CA, Laporte M, et al. "early" reoperation to treat complications following laparoscopic colorectal surgery: The

sooner the better. Surgical Laparoscopy, Endoscopy & Percutaneous Techniques. 2021;**31**:756-759

[148] Damrauer SM, Bordeianou L, Berger D. Contained anastomotic leaks after colorectal surgery: Are we too slow to act? Archives of Surgery. 2009;**144**:333-338 discussion 338

[149] Park EJ, Kang J, Hur H, et al. Different clinical features according to the anastomotic leakage subtypes after rectal cancer surgeries: Contained vs. free leakages. PLoS One. 2018;**13**:e0208572

[150] Numata M, Yamaguchi T, Kinugasa Y, et al. Safety and feasibility of laparoscopic reoperation for treatment of anastomotic leakage after laparoscopic colorectal cancer surgery. Asian Journal of Endoscopic Surgery. 2018;**11**:227-232

[151] Daams F, Luyer M, Lange JF. Colorectal anastomotic leakage: Aspects of prevention, detection and treatment. World Journal of Gastroenterology. 2013;**19**:2293-2297

[152] Newman RK, Dayal N, Dominique E. Abdominal compartment syndrome. (Update 2022 Apr 21). In: StatPearls (Internet). Treasure Island (Fl): StatPearls Publishing LLC; Jan 2022. Available from : https://www.ncbi.nlm. nih.gov/books/NBK430932/. Bookshelf ID: NBK430932 PMID: 28613682

[153] Perez D, Wildi S, Clavien PA. The use of an abdominal vacuum-dressing system in the management of abdominal wound complications. Advances in Surgery. 2007;**41**:121-131

[154] Carney DE, Matsushima K, Frankel HL. Treatment of sepsis in the surgical intensive care unit. The Israel Medical Association Journal. 2011;**13**:694-699

Section 3
