**2. MAYV, MADV, SLEV, ROCV, and OROV: neglected arboviruses**

Both alphaviruses and flaviviruses included neglected arboviruses. Nevertheless, given the importance of DENV and YFV, flaviviruses have been studied more, and even vaccines for a long time have existed for YFV [25] and recently for DENV [40]. However, there are no vaccines against alphaviruses for humans. Nevertheless, after epidemics of CHIKV in 2014–2015 in the America, their importance increased. However, as a group, the situation is worse regarding investigating orthobunyaviruses. Epidemics of CHIKV and ZIKV, as well as periodical outbreaks of YFV, especially in Brazil and Venezuela, have influenced the attention and research on these alphaviruses and flaviviruses [26, 27].

The region's MAYV, MADV, SLEV, ROCV, and OROV can be considered neglected arboviruses [41–44]. Even in most countries, such arboviruses are not under regular surveillance, laboratory investigation, and confirmation.
