**3.3 Molecular neuroendocrine control of egg production**

Major advancements have been achieved in the understanding of the neurohormonal control of egg production. In *R. prolixus*, a detailed model depicting the control of oogenesis, ovulation, and oviposition has been designed and elegantly reviewed by Lange and colleagues [13]. Post-genomics has allowed the identification and functional characterization of dozens of reproduction-related neuropeptide receptor families, processing enzymes, and neurochemicals. Historically, *R. prolixus* has been an important model, wherein the basics of insect physiology have been determined [67–70]. Interestingly, the integration of the post-genomics findings with the smartly designed early physiology experiments has allowed the elucidation and depiction of many aspects of the global endocrinal integration in this vector.
