**3. Conclusions**

Vector-borne diseases, particularly those involving virus transmission, continue to be a significant public health problem, especially in tropical countries, but even with climate change in also in subtropical countries. Still, in multiple countries, problems related to accurate diagnosis of the etiology of febrile syndrome are complex. That is in large magnitude related to arboviral pathogens, many of them neglected, as the case of MAYV, MADV, ROCV, OROV, and SLEV, among others. Therefore, after considering major arboviral diseases, such as DENV, CHIKV, ZIKV, YFV, VEE, and EEE, among others, epidemiological and clinical suspicion of them is critical to establishing a differential diagnosis, detecting them, and even identifying possible coinfections. At the same time, as there is a significant gap in knowledge about neglected arboviruses in Latin America, more research is needed to understand their implications and acute and non-acute clinical consequences and impacts.
