**6. Conclusion and future perspectives**

Development of biomaterials needs to focus on the biointerface construction to match the structure of the host tissue and to meet the mechanical requirements of specific tissue. In order to do that, metallurgic and additive manufacturing techniques present great potential in the development of Ti-Mg alloys, with complex shape formed by pores to be more biocompatible. It is critical to manipulate the surface by physical and chemical parameters to achieve the clinical purpose of the biomaterial, leading to a fast integration to the bone, due to the stimulating biological functions. In this review was showed that β -Ti-Nb-Sn alloy can be fabricated using Mg to create high content of porosity (20–38%), with an elastic modulus between 31 and 49 GPa close to bone tissue, and hardness close to commercial materials and higher than different parts of skeleton.

In this sense continuous studies and researches in this field is of great relevance for materials applied in life sciences.
