**4. Conclusion**

In this study, different interferometric optical sensors employed for the detection and quantification of OAMs are briefly reviewed (**Table 1**). The working principle, design and the important performance parameters including working range, sensitivity, and limit of detection were discussed in detail. Different materials analyzed in the sensors were outlined with special focus on sugar and protein being a representative OAMs. Two different interferometric arrangements, i.e., free space and optical fiber based optical sensors were discussed. It was


#### **Table 1.**

*Comparison of different OAMs analyzed by different interferometric arrangements.*

concluded that optical fiber based interferometry has mind blowing potential for highly precise sensing of OAMs with good sensitivity and can be applied in industrial and research and development applications.
