**5. Conclusion**

The study describes numerous computational tools that are widely used for drug and vaccine design against infectious viral diseases. However, improving ideas and methodologies can solve problems and provide system-level interconnected data. A promising idea accelerates the rational design of drug candidates that are used in the specific subfield. Here, we focused on computational methods that will help and provide a clear idea of modern drug and vaccine design approaches adequately.

#### **Acknowledgements**

The authors are in debt to King Abdulaziz University for their encouragements and unlimited support.

#### **Conflict of interest**

The authors declare no conflict of interest.

*Antiviral Drugs - Intervention Strategies*
