*3.5.2 Non-Hodgkin's lymphoma*

A study by J.E. Olson et al. reported 3.2 times increased risk of development of diffuse non-Hodgkin's lymphoma and extranodal disease in women with endometriosis as compared to those without it [37]. A similar observation was described by A. Melin et al. in their study using National Swedish Inpatient Register [38]. They linked this association to abnormal cellular and humoral immune function. As polyclonal B-cell autoimmune activation is observed in endometriosis, it is postulated to associate B cell lymphoma to B cell activation of endometriosis.
