**Abstract**

Although pharmacological therapy is a resource to be taken into account in rehabilitation medicine and physiotherapy (RMP), a series of therapies, techniques, and empirical practices have been available since time immemorial, some with scientific publications, which play an important role in healthcare current health worldwide. Some millennials like Traditional Chinese Medicine (TCM) and medicinal plants (MP), and other centenarians like Homeopathic Medicine (HM) and Osteopathic Medicine (OM). In the twentieth century, numerous medical techniques were developed, framed under the term of Biological Medicine in Europe such as Antihomotoxic Medicine (AM), Neural Therapy (NT), Catalytic Oligotherapy (CO). Throughout the twentieth and twenty-first centuries, the wealth of experiences and knowledge on the application of Growth Factors in therapeutics, Oxygen-Ozone Therapy, and other related techniques that have enriched medical practice has increased. The objective of this chapter is to highlight the convenience of incorporating unconventional therapies (UT) techniques with scientific evidence into RMP that enjoy efficacy, efficiency, and economic and environmental sustainability. It would be desirable to allocate more financial resources to continue researching these therapies, implement them in Health Sciences studies and continue working to comply with the maxim of medicine that is "primum non nocere" (first do no harm).

**Keywords:** rehabilitation medicine, integrative physiotherapy, unconventional therapies, integrative medicine
