*2.3.1.5 Antihypertensive activity*

According to a nonrandomized controlled trial, 57 patients who were given 2 g daily supplements of black cumin for one year showed a significant reduction in systolic, diastolic, and mean arterial BP, heart rate, TC, LDL-c, the fractions of TC/ HDL-c, and LDL-c/HDL-c, while serum HDL-c was suggestively raised when compared to baseline values and the control group. It was also used to assess the blood pressure-lowering capability and possible processes of *N. sativa* in a rat model, and it was discovered that the seed oil and nicardipine-treated groups had significantly lower blood pressure [71].
