**Table 2.**

*Algorithm for the treatment of DME.*

A.If starting focal macular laser and PFC.

	- If DME does not require further anti-VEGF, NV status should be re-evaluated.
	- If NV worsens significantly, it is suggested to decide on therapy according to Section 3.1 B (PDR without DME).
	- In case of new DME activity, it is suggested to reactivate anti-VEGF therapy.

Advantages and disadvantages of treatment options should be considered, as well as the individual conditions of the patient.
