**1. Introduction**

Polyvinylpyrrolidone (PVP) is widely employed as a multifunctional material and it was approved by the US Food and Drug Administration as a safe polymer for biological experiments due to its simple processability, biocompatibility, and nonantigenicity [1, 2]. The biomedical and pharmaceutical fields are among the most explored (**Figure 1**). Recently, PVP is considered as the most promising polymers, not only for the development of new pharmaceutical formulations [3, 4] but also for the optimization of several properties of bioactive glasses [2, 5]. This chapter highlights the link between PVP and some bioactive glasses. The multifunctional roles of PVP in pharmaceutical field were also discussed, focusing on the effect of PVP in terms of physical stabilization and solubility enhancement of various drug formulations in solid state (milling method as example).

**Figure 1.** *Schematic representations of various PVP applications [2].*
