**3.4 Spray drying**

Spray drying offers a quick and affordable method for getting rid of solvents and creating highly porous, fine powders that dissolve quickly. Rapid evaporation of the processing solvent during spray drying might result in the production of very porous, fine powder. Rapidly disintegrating pills can be made by spray drying [42]. This method uses a particulate support matrix, which is made by spray drying an aqueous composition comprising the support matrix and other ingredients into a highly porous and fine powder. The active components are subsequently added and the pills are crushed [43]. Hydrolyzed and nonhydrolyzed gelatins are used as supporting agents, mannitol is used as a bulking agent, sodium starch glycolate or croscarmellose sodium is used as a disintegrating agent, and an acidic and/or alkali material (e.g., sodium bicarbonate) is used to improve disintegration and dissolution [44].
