**5. Conclusions**

One of the main ways of preventing the development of obesity, managing body weight, and improving the indicators of physical condition is properly organized physical activity and a balanced diet. The combination of a balanced diet with increased physical activity will reduce body weight, whereas a change in lifestyle will help to maintain the achieved result. Physical activity contributes not only to body weight normalization but also has positive effects on metabolic disorders characteristic of people with obesity and overweight. The effectiveness of physical activity can be significantly increased by taking into account a set of biochemical, genetic, and microbiome markers. The presented findings of clinical trials and meta-analyzes
