**5. Herbal treatment**

Herbal medicine has been used for treatment of disease for more than 2000 years, and it has proven efficacy [4, 5, 15–17]. Many studies have confirmed that herbal medicine is effective in the treatment of obesity, but the mechanisms are not clear. In present work an attempt will be done to develop herbal formulation containing different types of spices. It is a doubtless fact that various plants from different families and several phytochemical constituents are responsible for the anti-obesity activity. Current treatment of obesity includes various marketed formulations which have hazardous side effects such as high blood pressure, agitation, diarrhea, sleeplessness, liver damage, rectal bleeding, faster rate palpitations, closed-angle glaucoma, Insomnia etc. which can be overcome by using herbal formulation. Herbal medicine has been used for treatment of disease for more than 2000 years, and it has proven efficacy. Many studies have confirmed that herbal medicine is effective in the treatment of obesity. But the mechanisms are not clear. In present work an attempt will be done to develop herbal formulation containing different types of spices. It is a doubtless fact that various plants from different families and several phytochemical constituents are responsible for the anti-obesity activity4 Natural herbs gives not only anti-obesity effect but also other health benefits, such as anti-diabetic and anti-hyperlipidemic activities. It is anticipated that the availability of many natural sources will provide a beneficial basis for developing novel anti-obesity products. Nature is loaded with dozens of herbs and spices—from the very common black pepper to the exotic turmeric. Along with amazing health benefits they have to offer, herbs and spices also add flavor and aroma to our food and dishes.

Research has also shown that herbs and spices have the potential to boost metabolism, promote satiety (read: contentment), aid weight management and improve the overall quality of diet. Very few researchers focus on exact molecular level mechanism responsible for anti- obesity activity. Therefore, the growing threat of obesity to global health is encouraging scientists and researchers to put more effort into finding an efficient mechanism of action at molecular level. It is anticipated that there is abundant room for further contributions by researchers to establish the molecular mechanism of new natural anti-obesity agents. Urgency of a novel, nontoxic means needs to be developed to control obesity. Various plant products have been found to be effective in controlling obesity. A good portion of fruits, vegetables, spices and herbs need to be included in the regular diet. Plant derived molecules or phytochemicals are blessed with strong anti-obesogenic, anti-carcinogenic and anti-inflammatory properties. Thus they may serve as a nontoxic and cost-effective method to tackle obesity. These molecules target various pathways that are intricately linked to the process of adipogenesis. This review aims to elucidate the beneficial role of dietary food nutrients in control of obesogenicity. Following are the herbs which stimulate leptin in obesity management.

### **5.1 Cinnamon**

Cinnamomum-verum (cinnamaldehyde)

Cinnamon is most widely used and popular weight loss herbs due to its sugar stabilizing potential which rapidly increase rate of metabolism of fats and rapidly reduces hunger pangs which has excellent for obesity management.

### **5.2 Ginger**

### *Zingiber officinale* (6-gingerol)

Ginger acts as a potential body cleanser which remove the food logged in the digestive system and avoid fat storage resulting in to weight loss and obesity management.

### **5.3 Cardamom**

### *Elettaria cardamomum* (I,8-cineole)

Cardamom boosts metabolism and helps the body burn fat more effectively and Managing conditions like indigestion, constipation, and water retention, elaichi makes for an important weight loss. Cardamom improves rate of metabolism which results in to increasing potential of our body to burn fat which ultimately helpful for weight management.

### **5.4 Turmeric**

### *Curcuma longa* (Curcumin)

Curcumin is safest yellow orange colored material obtained from turmeric having potential role in increase in rate of metabolism, stimulate leptin and adiponectin. Curcumin drastically reduces rate of fat formation and accumulation which ultimately lower total body fat which avoids weight gain.
