**5. Conclusions**

Obesity is a chronic condition with considerably increased morbidity and mortality. Obesity has complex genetic, physiological, behavioral, sociocultural, and environmental etiologies. Hence, a multi-pronged and comprehensive strategy is critical. Lifestyle and behavioral modifications are key in the treatment of obesity, combined with diet, exercise, and behavioral therapy to achieve adequate WL. Pharmacology should be considered for individuals not responding to lifestyle modifications or those who have difficulty maintaining the weight loss initial achieved by lifestyle modifications.
