**1. Introduction**

The uptake of the Radiopharmaceuticals in the organ of interest makes the functional evaluation of that organ feasible. Not only that the radiopharmaceutical uptake in the pathological conditions depends on the blood supply to the organ, bolus injection of the radiopharmaceutical and the functional integrity of the organ. When there is increase in blood supply and integral functionality in a lesion will lead to focal increase in radiopharmaceutical uptake resulting in the Hot spots. In those situations where there is reduction in the blood supply to the organ and decreased functional integrity will result in photopenic or photon void lesions. Conventionally scintigraphic imagery is being inferred by graphical inspection of the photographic imprints and comparing with the known normal distribution pattern in the organ of interest.

The advancement of digital scanning technologies have made it easier to measure the scintillations by quantifying the per pixel counts of the intended regions. In addition, the post-processing and PACS transmission characteristics have been the

major reason behind the Dicom compatible graphics. The phrase "SCINTIMETRY" means the number of scintillations taking place in intended regions in scintigraphic imagery that has been covered in the study. Basically, "Scintimetry" is the combined term of "Scintillation + Metric".
