**8. Conclusions**

Radiopharmaceutical therapy is a safe and effective targeted approach to treating many types of cancer. Compared to other systemic cancer treatment options, RPT has shown efficacy with minimal toxicity. Different types of radionuclides

#### *Radiopharmaceuticals in Modern Cancer Therapy DOI: http://dx.doi.org/10.5772/intechopen.99334*

relevant to the purpose are β-emitters, Auger electrons, and α-emitters. However, the targeted α-emitter has potential advantages over β-emitter therapy due to the high energy and short path length of α emissions causing double-stranded breaks in DNA and the relative tolerance to cell cycle effects and hypoxic conditions. Radionuclides are coupled to ligands that recognize and bind the tumor-associated molecules, ensuring the precise targeting of cancerous cells that can be used for therapeutic approaches and live-monitoring of treatment efficacy. Different radioligands are developed for uniquely targeting molecular receptors or intracellular components that currently lead to planning personal patient-tailored therapy in modern cancer therapy management.
