**Acknowledgements**

The authors thank the laboratory team for their technical assistance. The researchers were supported by Sao Paulo Research Foundation (FAPESP: #2015/22814-5 and #2015/17275-8), MicroRNA Research Center (NAPmiR, University of Sao Paulo), National Council for Scientific and Technological Development (CNPq: #313479/2017-8), and Coordination for the Improvement of Higher Education Personnel (CAPES-PROEX: #88887.484856/2020-2100 and #88887.640701/2021-2100).
