**7. Conclusions**

This chapter represents a review of the literature on physical inactivation of SARS-CoV-2 and other members of the *Coronaviridae*. While physical approaches include X-irradiation, electron beam irradiation, and high pressure treatment, literature on those approaches for inactivation of coronaviruses were not identified during the search. Therefore, the chapter discusses only gamma irradiation, UVC irradiation, and heat inactivation. The *Coronaviridae* in general, and SARS-CoV-2 in particular, appear to be quite susceptible to each of these three physical inactivation approaches. The various approaches have utility for different applications. For instance, of the three approaches, UVC is most useful for indoor air

decontamination, each is useful for liquid or surface inactivation. Each approach has its advantages and disadvantages, which were discussed for the benefit of the reader.
