**6. Conclusions**

In order to expand the known set of virucidal agents with efficacy for SARS-CoV-2, we conducted virucidal efficacy studies on Ag<sup>+</sup> with and without 26% (w/w) ethanol, according to the ASTM E1052 standardized suspension methodology [4]. The Ag+ formulation with low concentrations of ethanol should be less flammable than 70% ethanol at the time of use or at the time of storage and during shipping. The formulation without ethanol proved effective for the enveloped SARS-CoV-2 virus, while efficacy for non-enveloped viruses such as FeCV required formulation with 26% ethanol.

To our knowledge, this is the first report of the virucidal efficacy of Ag<sup>+</sup> formulations, evaluated using standardized ASTM methodology, for inactivating SARS-CoV-2. From the viewpoint of infection prevention and control, effective surface disinfectants such as the Ag<sup>+</sup> ion formulations discussed in this chapter represent a possible intervention for interrupting the transmission of SARS-CoV-2.
