**Abstract**

As a counterargument to the Cartesian split that has impacted both speculative and practical fields of knowledge and culture, we propose Peirce's doctrine of synechism to show the continuity in the semiotic activity that moves from the body as an Interpretant to the emergence of another Interpretant called the "self." Biosemiotics, a nascent field of interdisciplinary research that tackles inquiries about signs, communication, and information involving living organisms is used as the framework in the discussion. The main question of whether a non-material "self" can emerge from a material body is tackled in many stages. First, the biosemiotic continuum is established in the natural biological processes that takes place in the body. These processes can be taken as an autonomous semiotic system generating the "language" of the body or the Primary Modeling System (PMS). Second, synechism is also observed in the relationship between the mind and the body and this is evident in any physician's clinical practice. The patient creates a Secondary Modeling System (SMS) of how she perceives what the body communicates to her regarding its state or condition. Finally, the question about whether the emergence of "self" is synechistic as well is tackled. There is one organ from which emerges an Interpretant that is capable of generating a dialog between a Subject, that is the "self," with its Object, and that is the brain. It is the primordial seat of specifically human activities like thought and language. The recent theory on quantum consciousness supports the doctrine synechism between the body as Interpretant to the "self" as Interpretant. This synechism is crucial for the creation of Secondary Models of "reality" that will, in turn, determine the creation of Tertiary Models more familiarly called culture.

**Keywords:** semiotics, biosemiotics, synechism, Charles Sanders Peirce, Peirce-Sebeok modeling systems
