**Abstract**

The moth *Lobesia botrana* (Denis and Schiffermüller) (Lepidoptera: Tortricidae) is one of the principal pests of the grapevines (*Vitis vinifera L*.). His larvae feeds from grape, reducing production and increasing susceptibility to fungal infections. This makes it one of the most economically important pest insects in wine and table grape exporting countries. This chapter will describe the distribution, biology, and behavior of *L. botrana* regarding its host, the grapevine, along with its control via the use of natural enemies, entomopathogenic microorganisms, MD (mating disruption) and chemical control. Finally, we will describe an integrated management strategy based on monitoring, MD, and biological control using entomopathogenic microorganisms. This strategy could be useful as a basis for integrated pest control plans in various regions worldwide.

**Keywords:** *Lobesia botrana* (Denis & Schiffermüller), grapevine, integrated pest management, biological control, ethological control and chemical control
