*3.3.2.1 Harmful effects of pesticides on human health*

Acute intoxication is caused by high dosage of organophosphorus (OP) insecticides. Gastrointestinal discomfort, perspiration, muscle spasms, muscle weakness, bronchospasm, high blood pressure, bradycardia, central nervous system depression, and coma are all indications of this type of poisoning. People who have been exposed to OP for a long time develop a pesticide-related sickness, which can include headaches, dizziness, abdominal discomfort, nausea, blurred vision, vomiting, and chest tightness [100]. Insecticides containing carbamates have been implicated with the development of respiratory illnesses. Organochlorine (OC) based insecticides pose the most serious and dangerous harm. They are difficult to degrade because they are lipid-soluble and have a high rate of persistence. Infertility, genital malignancies, tumors of the reproductive organs, neurotoxicity, and immunotoxicity are among the harmful effects of these chemicals [101].
