**7. Conclusion**

Though work on Rare actinobacteria and bioactive compounds from them is gathering momentum, not many studies are targeted towards isolation and identification of AQS compounds from rare actinobacteria and this research area is still in its infancy. These studies may lead to novel bioactive compounds that can act against bacterial quorum sensing systems. These agents can attenuate the virulence of the pathogens without challenging their growth, thereby preventing the emergence of resistant strains.

Such potent anti-quorum -sensing compounds may lead to the development of alternative therapies to address the glaring problem of antibiotic resistance.

This would be of immense medical and commercial benefit.
