**A. Appendices and nomenclature**

Leu10, Gly11, Gly13, Ser14, Gly15, Gly16, Val34, Asp35, Val36, Phe44, Ala46, Ala47, Gly50, Thr51, Cys52, Val55, Gly56, Cys57, Lys60, Lys61, Gly125, Phe126, Gly127, Ala128, Arg138, Ser140, Glu141, Pro143, Ala159, Thr160, Gly161, Ser162, Trp163, Pro164, Thr165, Thr177, Ser178, Asn179, Phe182, Tyr198, Ile199, Glu202, Phe203, Met282, Leu283, Ala284, Ile285, Gly286, Arg287, Arg290, Thr293, Leu294, Gln295, Ile325, Gly326, Asp327, Val332, Met333, Leu334, Thr335, Pro336, Val337, Ala338, Ile339, Asn340, Arg355, Thr357, Asp358, His359, Thr360, Lys361,Val362, Ala363, Cys364, Ala365, Phe367, Pro435, Glu436, Ile438, Gln439, Gly442, Ile443, Lys446
