**Doxycycline**

Doxycycline, [10] though it's not the first choice of medication, still is considered equally efficacious to pentavalent antimony. It is known to have good intracellular penetration and acts directly on the body of leishmania. Due to its anti-inflammatory effect, there will be immediate relief in signs of local inflammation. Oral route of administration, low cost, easy availability and ack of major adverse effects, make doxycycline a good alternative option in the treatment of leishmaniasis. It is given in the dose of 200 mg/day.
