**1. Introduction**

The main goal of treatment is parasite eradication and clinical healing. Generally, parasite eradication is seen long before clinical re-epithelialization. Treatment for each case varies so it needs to be individualised depending upon various factors affecting the treatment outcome [1] (**Table 1**). The clinical manifestation of leishmaniasis can be broadly classified as cutaneous and visceral types. In this chapter, treatment for various clinical manifestations will be discussed in detail.

