**7. Paromomycin**

It is an [6] aminoglycoside antibiotic that has been tried in the treatment of visceral leishmaniasis in India and Africa. It shows a promising cure in areas with species resistant to SSG. Moreover, it is less expensive, easy to administer than AMB.

**Dose**: 11 mg/kg/day given as intramuscular injection for 21 days.

**Adverse drug effect:** ototoxicity, injection site pain, the reversible elevation of serum transaminase, renal toxicity (rare).

Adverse effects and laboratory monitoring of the above mentioned drugs has been discussed in (**Table 4**).


#### **Table 4.**

*Adverse effects and laboratory monitoring of major anti-leishmanial drugs.*
