**12. Commercially and clinically available liposomal based products**

Various attempts have been made in research to develop novel liposomal formulations for commercial importance and some are under clinical trials. Liposomes have gained their commercial importance with Intravenous formulations. However some recently developed liposomal formulations which are under clinical trials is Arikace (Amikacin for lung infections) [117, 118] which can be given as subcutaneous injection or inhaled as aerosols. Apart from intravenous route and nasal route, the research is being focused and investigated on liposomal formulations for topical route by applying new strategies in the preparation of cosmetics such as skin creams, anti-aging creams, after shave, lipstic, sun screen and make-up [119]. The liposomal-based drugs that are available in market and are under clinical trials are shown in **Tables 1** and **2** respectively.

#### **13. Conclusion**

In the last decade, liposomes have become much popular due to research and commercial importance. They offer several advantages for the delivery of different molecules in various routes of administration. Hence the regulatory agencies through the globe is also implemented the subject of liposome into their guidelines. In conclusion, continuous efforts are going in the area of liposome technology to make them better for drug delivery.

#### **Acknowledgements**

The authors are thankful to University Grants Commission (UGC, New Delhi, India) for providing financial assistance for carrying the research work. The authors would like to acknowledge M/s. GITAM Institute of Pharmacy, Gandhi Institute of Technology and Management (GITAM) Deemed to be University, Rushikonda, Visakhapatnam, Andhra Pradesh, India for providing facilities and giving support to conduct this work.

*Smart Drug Delivery*
