**8. Conclusion**

The growing number of resistant infectious agents is a threat to the world. Various screening strategies such as vHTS, HTS (phenotypic cell-based 2D/3D screening), and therapeutic approaches (nanotechnology, synergistic combinations) for drug repurposing may be employed for rapid identification and formulation of new therapeutics against infections. These approaches are especially useful during emerging outbreaks and pandemics of infectious diseases such as MERS, SARS, SARS-CoV-2, and Ebola viruses because it is highly impractical to develop vaccines and therapeutic agents in a short period. Nevertheless, there is an important question that needs to be addressed by the scientist working toward a drug repurposing approach. What if the existing pharmacopoeia for repurposing will get exhausted one day?
