**7. Conclusions**

The interest in studying protein interactions, their variations, and their constituent's effects on pathological conditions has grown within the last few decades. These interests are behind, for instance, the increasing examination of the application of mass spectrophotometer (MS)-based experimental analyses of model systems to explore heterogeneous PPI networks and protein complexes, which will promote drug repurposing within the context of human diseases.

The use of other robust technology such as NGS in the study of biological processes, which would have otherwise remained elusive, is the driver for the actualization of personalized medicine for which drug repurposing form a central aspect. Molecular interactions at both the DNA-RNA/protein level are sequined with the SNP, epigenetics, mutations causing variants, and other factors emanating from our immediate environment e.g. stress. Technological advancement discussed in this chapter is all part of the process for science and scientists to understand the biological phenomenon that governs life at the molecular level.

Many disease variants resulting from SNP, single point mutation, and RBP role in disease manifestation are discussed with a view to heighten our thinking towards drug repurposing, the uptake of phytomedicine, and bioactive compounds in the management of various disease phenotypes.

*Recent Progress in Drug Repurposing Using Protein Variants and Amino Acids in Disease… DOI: http://dx.doi.org/10.5772/intechopen.102571*
