**4. Genome-wide association studies (GWAS)**

This is a computational approach aimed to identify genetic variants associated with common diseases to unveil disease mechanism, novel targets, between diseases, to be treated by repurposed drugs [60]. This approach has been used to find

matching gene targets already identified for coronary artery disease with information three different drug-target databases (DrugBank, Therapeutic Target Database, and PharmGKB) to select potential repositioning candidates [61]. However, this approach is having certain limitations its utility at present is not much clear [60].
