**2. Clinical factors and male infertility**

Anatomical disorders distract the ability of man to produce viable sperms. Fertility centres regularly work with the specialists to diagnose the anatomical causes responsible for Male infertility [8]. Some of the common forms of anatomical factors include.

### **2.1 Varicocele**

The anatomical issues can surface as varicocele, a condition in which the enlargement of testicular veins adversely affects the sperm quality and production. In certain cases varicocele can even impair the development of testicles. Varicocele can lead to the increased state of the temperature of testes and thereby causes the

reflux of metabolites (toxic) of adrenal vein to the left kidney [9]. It is reported that 40 percent of infertile men have varicocele being diagnosed as the primary reason of the ailment.
