**5. Conclusion**

The study findings confirms that TNF-α, plays a positive role in the pathogenesis of T2DM and can act as early prediction biomarkers which can prevent T2DM in this population. Further studies on the wider range of inflammatory mediators in association with other biochemical, immunoassay and hematological parameters are needed to establish role of inflammatory markers as early prediction biomarkers which can prevent T2DM.
