**Acknowledgements**

Some of the comparative studies between theobromine and fluoride was conducted by Mr. Arman Sadeghpour as part of his Ph.D. dissertation under the strict guidance of Drs Tetsuo Nakamoto, and William B. Simmons Jr. and Mr. Alexander U. Falster. The authors met Mr. Joseph Fuselier who was organizing a biotechnology group interested in the New Orleans area after Hurricane Katrina, August, 2005. He has much-needed experience in the industrial aspects of biotechnology. Mr. R. Jantzen Hubbard and a little later, Ms. Natalie Borchers and Mr. Andrew Lisle Fuselier joined the group to develop and operate the non-fluoride toothpaste, now known to be chocolate toothpastes. The authors appreciate Ms. Julie Schiavo, librarian at LSU Health Sciences Center, for her help with various references.
