**Abstract**

The aim of orthodontic treatment is to improve the esthetics of the teeth and face, to provide a beautiful smile, and an adequate and permanent chewing function. In individuals with insufficient oral hygiene, demineralization begins in the mouth with a very low pH value, and as a result, white spot lesions formed by decalcification of the enamel layer can be seen during orthodontic treatment. Since lesions are the first stage of caries formation, it is possible to stop caries development at this stage. Many methods, such as improving oral hygiene, regulating diets, fluoridated agents, laser, casein phosphopeptide, and microabrasion, are used in the treatment of white spot lesions. Preventive methods are of great importance in terms of preventing future tooth loss and reducing the treatment process. The purpose of this article is to manage white spot lesions in orthodontic treatment and to examine risk factors and preventive methods based on the latest evidence.

**Keywords:** white spot lesion, orthodontic treatment, conservative methods, demineralization
