*4.2.1.1.2 Inorganic template-assisted synthesis (ITAS)*

In this method, firstly, the core material is coated by employing an inorganic material like SiO2 as binding sites for shell MOF, or metal oxide as the metal source for the shell MOF growth, and then synthesis of MOF will be implemented. Although in contrast CAAS procedure applying metal oxide prepare some advantages due to their act as metal source or protection of reactive nanoparticles in the core, there are some restrictions to fabricate wrapped nanoparticles owing to the shell MOF chemical stability will be endangered through the etching of the sacrificing metal oxide. Despite the fact that SiO2 can play as a useful protective layer, it can represent as a sacrificial layer to fabricate a yolk-shell structure by conducting selective etching of SiO2. In addition, in some cases, metal oxide/metal(0) nanoparticles have also been utilized as sacrificing agents to fabricate core-shell architectures [53].
