**3.2 Ascorbic acid**

Another randomized trial of preparing a biocomposite osteogenic nanofiber was developed with the incorporation of polycaprolactone, hydroxyapatite, dexamethasone, gelatin, beta-glycerophosphate, and ascorbic acid along with titanium implants was developed so that it mimics the bone extracellular matrix and eventually induced osteogenesis in the peri-implant niche and also regenerates the osseous tissue. This implant was worked on rabbit models and the results revealed that a coating of osteogenic nanofibrous tissues significantly increased the magnitude of osteogenesis around the zone of peri-implant tissue and also favored the dynamics of osseointegration [33].
