**8. Dataset description**

To conduct VBM-based PD detection on MRI on separate datasets, one for men and another for women, the largest publicly available collection of MR images is the *Parkinson's Progression Makers Initiative* (PPMI) dataset. This dataset is the result of collecting clinical data (including images) for PD research around the world. Clinical data includes genomics, patient data, and imaging data. The PPMI dataset is publicly shared to accelerate research discoveries to assists the treatment and diagnosis of PD. PPMI's T1-weighted MR images have been applied to VBM-based PD detection. T1-weighted MR images were generated by using a 1.5–3 T scanner with (1) a scanning time between 20 and 30 min, (2) a slice thickness of 1.5 mm or less, and (3) at three different views, axial, sagittal and coronal. The MR images were obtained from 226 men with PD, 86 male controls, 104 women with PD, and 64 female controls.
