**Knowledge area co-editors**

Aura Matilde Jiménez Garduño Nelly Ramírez Corona José Luis Sánchez Salas Enrique Ajuria Ibarra Roberto Rosas Romero

We continue with this series discussing on research topics related to the fields of Food Science, Intelligent Systems, Molecular Biomedicine, Water Science, and Creation and Theories of Culture. Our aims are to discuss the newest topics, theories, and research methods in each of the mentioned fields, to promote debates among top researchers and graduate students, and to generate collaborative works among them.

The interactions of recognized specialists in each field and graduate students, through different meetings, generated very interesting discussions, which are presented in this book. Thus, Dr. Luis A. Pardo, from the Molecular Biology of Neuronal Signals Max Planck Institute for Experimental Medicine, contributes with the article titled "Targeting the voltage-gated potassium channel Kv10.1 for cancer therapy". Dr. Marco Carli, Associate Professor of the Department of Engineering at the Università degli Studi 'Roma TRE', Roma, Italy, explored, along with his co-author Federica Battisti, the quality of experience for immersive media with the work "QoE and immersive media: a new challenge". Dr. Sandra Harding, Distinguished Research and Emeritus Professor of New York University, wrote the article "Strong objectivity for new social movements". Dr. Vijay P. Singh, Distinguished Professor, Regent Professor, and Caroline and William N. Lehrer Distinguished Chair in Water Engineering at Texas A&M University contributes with the article "Challenges in flood management". Dr. R. Paul Singh, Distinguished Professor of Food Engineering of the Department of Biological and Agricultural Engineering at University of California wrote the article "A quest for sustainability in the food enterprise". Finally, graduate students of the Universidad de las Américas Puebla further present their key findings in a series of articles.

We believe that interactions between students and high-level researchers of different areas contribute to the creation of multidisciplinary points of view generating the advancement of science.

The number and impact of water-related natural disasters has increased since the middle of last century. As result of increased climate variability and the effects of global warming, the hydrometeorological risk has increased and spread, while the resilience of societies, in many cases, is not adequate. Consequently, the risk has increased. Floods and droughts, particularly in a changing climate, require greater understanding to generate better forecasts and proper management of these phenomena. Mexico, like other countries in the world, and of course in Latin America and the Caribbean region, suffers from both weather extremes.

The UNESCO Chair on Hydrometeorological Risks, held at the University of Americas Puebla, is devoted to the analysis, measurement, modelling and management of extreme hydro-meteorological events in the context of a more urbanized world, climate change and further vulnerable regions. Focused on the development of basic and applied research for the design of adaptation and mitigation measures, dissemination and preparation of decision makers as well as the public. In its activities keeps a gender focus, directed in particular to reduce the vulnerability of women to hydrometeorological disasters.

The Chair acts in the following fields:


A detailed description of the UNESCO Chair on Hydrometeorological Risks, members and publications, can be obtained at its Website https://www.udlap.mx/ catedraunesco/

The Chair publish a quarterly Newsletter, in Spanish and English, that can be consulted at https://www.udlap.mx/catedraunesco/newsletters.aspx


**VII**

Contents

*Federica Battisti and Marco Carli*

*Luis A. Pardo*

*Sandra Harding*

*Vijay P. Singh*

*R. Paul Singh*

*and Irene Vergara Bahena*

*and Miguel Ángel Méndez-Rojas*

Targeting the Voltage-Gated Potassium Channel Kv10.1 for Cancer

Therapy 1

QoE and Immersive Media: A New Challenge 9

Strong Objectivity for New Social Movements 21

Challenges in Flood Management 31

A Quest for Sustainability in the Food Enterprise 45

in a Prostate Cancer Cell Line 57

Designing Magnetic Mesoporous Nanoparticles for Cancer Therapy 65

Analysis Techniques 75

Network Intrusion Detection Using Dendritic Cells and Danger Theory 89

Automatic Terrain Perception in Off-Road Environments 107

of Parkinson's Disease with Machine Learning 121

A Systematic Review of Sensitivity Analysis of Activated Sludge Modeling 135

Microbial Photobioelectrochemical Systems: A Scoping Review 163

A Review 193

Evaluation of the Cytotoxic Activity of a Species of the Buddleja Genus

Exoplanet Research Using Machine Learning and Multiresolution

*Miguel Jara-Maldonado, Vicente Alarcon-Aquino and Roberto Rosas-Romero*

Analysis of Voice and Magnetic Resonance Images to Assist Diagnosis

*Rafael Andrés Borobio-Castillo, José Manuel Cabrera-Miranda,* 

*Luis Erick Coy-Aceves, José Luis Sánchez-Salas, Mónica Cerro-López,* 

Methods for Persistent Organic Pollutants Removal in Wastewater:

*Sofía Isabel Cuevas Cianca, Luis Ricardo Hernández* 

*Jessica Andrea Flood-Garibay, Kenneth J. Balkus Jr* 

*David Limon-Cantu and Vicente Alarcon-Aquino*

*Gabriel Solana-Lavalle and Roberto Rosas-Romero*

*Alberto Vargas-Hidalgo and Benito Corona-Vásquez*

*Miguel Ángel Méndez-Rojas and Benito Corona-Vázquez*

*Valérie Pihen and Jose Luis Sanchez-Salas*

*Ethery Ramírez-Robles and Oleg Starostenko*
