**Funding**

This manuscript is a review and we did not have funding.

### **Competing interest**

The author declare no competing interest.

### **Ethical approval**

This article does not contain any studies with human participants or animals performed by any of the authors.

### **Nomenclature**


IC50 Hal-maximal Inhibitory concentration DM Dry Metter LD50 Half of a Lethal Dose DW Dry Metter CC50 Mean Cytotoxic Concentration i.p. Intraperitoneal S.C. Subcutaneous G-A Galphimine A G-B Galphimine B G-E Galphimine E C.N Kinetine
