**10. Effectiveness of maintaining logbook, training and SOPs**

Knowing the difference between a laboratory logbook and a laboratory notebook is very much effective to proceed with laboratory work. Logbook keeps details, usually in a tabulated format on handling and use of equipment, users, time of use, the purpose of use, and watched comments in case any. Other than, the research facility notebook or diary contains whole experimental details (for investigation and analysis), all the readings, results of any calculation, eventually all the supplementary data (graphs, spectra, or chromatograms) preserved in note book. Every research facility action related to the utilization of testing equipment, laboratory environmental records (temperature, humidity, atmospheric pressure, and exposure to light), weighing balance logs (analytical balance is the foremost used device in any research facility), material consumption, chemicals, details of suppliers and supplies are conserved as a proof record. Depending on the work nature vary the types of logbooks. Both notebooks and logs play a vital role in decision making or identify the problems or take part to fix the false result. During an audit, a logbook helps to convince the auditor because it provides evidence-based data. Periodically maintenance, operated by trained staff, calibration, and servicing of instruments increase the shelf life of the instrument, and these logs are stored as a proof document for safe work. Standard operating procedures (SOPs) based work has the same impact on research. On the other hand, training is significant for the advancement of the skills and knowledge of laboratory staff. In a training log the topic of training, date and time, name of trainer and trainees, effectiveness, and also the performance of individuals is reserved [34, 45]. Does every detail clarify in SOP like how to operate an instrument, test, or a machine? How will be eligible to perform? How to monitor (lab,

*A Brief Concept of Cell Culture: Challenges, Prospects and Applications DOI: http://dx.doi.org/10.5772/intechopen.99387*

work, test, etc.) and keep the record? How to calibrate and when? Who certifies and how? How to use chemicals? In a word SOP is fundamental. It is an ideal practice to have procedures for maintaining and controlling laboratory stocks which are clearly defined in specific SOP.
