**10. Conclusion**

The EVs are secreted from various types of cells and are regulated by physiological conditions and other pathological conditions including cancers. EVs are considered to be attractive resources for cancer biomarker development. More research to identify potential biomarkers should be performed. This may provide more clues for elucidating the biological functions of EVs in cancer development as well as predicting the disease progression. These researches about the EVs will again offer valuable information to increase our understanding into the pathology of cancer and provide the novel ways to advance the diagnosis and prognosis of cancers.
