**2.2 How do extracellular vesicles impact epithelial ovarian cancer?**

EVs provide a pertinent target for research because EOC cells exploit EVs for intercellular messaging. By hijacking the EV communication system, cancer cells distort key biological processes that enhance cancer survival, including angiogenesis, immunity, apoptosis, inflammation, migration, invasion, and even activation of secretion of tumorigenic factors by stem cells [1]. Malignant cells dramatically increase EV synthesis, manipulating crucial intercellular communication, exerting control over the tumor's surrounding environment, and transforming this microenvironment into a tumorigenic niche that facilitates chemoresistance and progression of disease [10]. Since EVs affect many aspects of EOC propagation and spread, they are suitable candidates for the development of new diagnostic and therapeutic management options.
