**Appendix**


#### **Table A1.**

*Topological architecture of the differentially expressed genes associated with APAR mechanisms in astrocytes. All gene regions have been obtained from ENSEMBL (GRCh37/hg19). All the TAD described contained promoters, enhancers and promoter flanks.*

*Multi-Omic Epigenetic-Based Model Reveals Key Molecular Mechanisms Associated… DOI: http://dx.doi.org/10.5772/intechopen.100133*
