**3.3 α Adrenergic Agonists**

Ocular surface the effects include ocular allergy, conjunctival follicles. Allergic reaction has been observed in up to 15% in chronic treatment with brimonidine [14].

## **3.4 Carbonic anhydrase inhibitors**

Ocular surface side effects include allergic conjunctivitis and periorbital dermatitis [14].
