**9. Clinical effect with the S.B.I.T. treatment**

We clinically evaluated the results obtained by using immunotherapy and we observed different facts recorded on about 7,500 cases treated since 1963 till 2016.


Some of these effects (sequestrum resorption or demarcation, reduced articular rigidity, increased repairing capacity) may be explained only by hypothesising a stimulating action on the reticuloendothelial cells that are able to differentiate themselves in different tissues [9].

We studied also possible differences between children, known for their evolutive receptive potentiality, and adults leaving the kind pf suffered infection out of consideration.
