**16. Conclusions**

By comparing the results obtained in chronic osteomyelitis (both hematogenous and post-traumatic) before introducing immunotherapy and reconsidered afterwards, after having acquired a long experience in its administration, we feel following conclusions have to be drawn.


We may conclude that Specific Bacterial Immunotherapy (S.B.I.T.) has to be considered an important defence, that does not exclude, but has to be associated to antibiotico therapy and even more to surgery. The obtained positive results shall be studied with complex research methods, as the concept "immunity messenger" opens therapeutical approaches, still difficult to evaluate.

*Specific Bacterial Immunotherapy in Treating Chronic Osteomyelitis DOI: http://dx.doi.org/10.5772/intechopen.98751*
