*6.3.4 Carotenoids and flavonoids*

Supplementation of carotenoids and flavonoids causes an immunostimulator effect in the form of an increase in Th cells and NK cells, IL-2 receptors. Research has shown the ability of carotenoids to influence the production of cytokines, namely TNF alpha and IL-1, and T cell proliferation, as well as flavonoids to influence inflammation, cytokine production, lymphocyte and granuloside production through mechanisms of protection against free radicals, regulation of NO and arachidonic acid metabolism [85].
