**Abstract**

Atrial Fibrillation (AF) is an early and common occurrence during septic shock, accounting for 25–30% of admissions. Conventional cardiovascular risk factors do not generally increase its incidence, especially in cases of new-onset AF. Inflammation during the sepsis process has been postulated as a possible trigger. Detrimental effects of AF result in prognosis worsening, even when the probability for a negative outcome has been adjusted for severity of illness. New-onset AF (NOAF) has been associated with greater mortality rate than preexisting chronic AF. Early cardioversion has not uniformly improved hospital outcomes. In this review, the incidence, prognosis and management of AF in septic shock patients are summarized.

**Keywords:** atrial fibrillation, septic shock, sepsis, antiarrhythmic therapy, cardioversion, critical care
