**3. Clinical features**

Unlike adults, children are likely to be symptomatic, the prevalence of symptomatic children is from 50–70% [44]. The most common clinical presentation is right upper quadrant abdominal pain [usually after meals] which may be radiating to the right shoulder, nausea, vomiting and occasionally fever. Symptoms are more seen if cholelithiasis is associated with complications like cholestasis, cholecystitis, and cholangitis, in these settings additional symptoms like icterus and Murphy's sign can be seen. In infants, mostly cholelithiasis is asymptomatic and incidentally diagnosed on abdominal ultrasound.
