**6. Conclusion**

In conclusion, the COVID-19 pandemic poses some unique challenges for child health and learning. In relation to child health, Multisystem Inflammatory Syndrome in Children (MIS-C) is a rare but severe complication of COVID-19 related to acquired immune responses that requires further research. Despite limited studies to date to define therapeutic guidelines in children, consensus recommendations from multiple organizations recommend the use of immunomodulatory therapies, antiplatelet and anti-coagulant therapies. Furthermore, considerations for safe return to the classroom such as strategies for optimized student to teacher ratios, hand washing, social distancing, sibling pairing and staged re-opening strategies may facilitate child learning in the setting of this evolving pandemic. Further research into efficacy of these proposed interventions will be necessary to inform evidence based guidelines for the prevention and management of COVID-19 in children.
