**Abstract**

When SARS-CoV-2 began to spread, older adults experienced disproportionately greater adverse effects from the pandemic, including exacerbation of pre-existing physical and cognitive frailty conditions. More severe complications, higher mortality, and concerns about disruptions to their daily routines and access to care. Knowledge about the impact of COVID-19 on the brain is rapidly accumulating and this is reflected in the increasing use of the term "*neurocovid*". Co-involvement of the central and peripheral nervous system had already been observed in SARS patients, but COVID-19 seems to invade it with greater affinity than other coronaviruses. This chapter provides an overview of the expanding understanding of the multiple ways in which COVID-19 affects the human brain, discuss the likelihood of longterm sequelae of neurocovid, and their implications for cognitive functions and behaviors in the elderly.

**Keywords:** COVID-19; SARS-CoV-2, neurocovid, long term pandemic fatigue, mechanisms of brain damage, brain dysfunction, neurology, neuropsychology, neuropsychiatry, cognitive dysfunctions, mood changes, anxiety, depression, social isolation, frailty, elderly, older adults
