Contents



**III**

**Chapter 18 289**

Diagnosis and Management **299**

**Chapter 19 301**

**Chapter 20 317**

**Chapter 21 333**

**Chapter 22 347**

**Chapter 23 357**

**Chapter 24 369**

**Chapter 25 385**

**Chapter 26 397**

**Chapter 27 419**

**Chapter 28 429**

Myths Surrounding Covid-19 Vaccine Candidates: A Guide to Fight Back

Evolution of Diagnostic Methods and Prevalence Detection of COVID-19:

*by Sara Jimeno, Alejandro Peixoto, Sara Velázquez, Paula Sol Ventura,* 

*Salvador I. García Adasme and Alejandro López-Escobar*

Myths: Barriers to Fighting the COVID-19 Pandemic *by Olabode Omotoso, Teibo John and Gbenga Ojo*

*by Fermín Jesús González-Melado and María Luisa Di Pietro*

*by Mayank Kapoor, Prasan Kumar Panda and Vivek Mohanty*

Home Care as a Safe Alternative during COVID-19 Crisis *by Heloisa Amaral Gaspar and Claudio Oliveira Flauzino*

Tackling COVID-19 through the One Health Approach *by Ayodele Oluwaseun Ajayi, Olawale Peter Odeleye* 

*and Oluwabukola Atinuke Popoola*

COVID-19 and Catastrophic Antiphospholipid Syndrome

Fighting COVID-19: The Medical Laboratory Involvement *by Obeta M. Uchejeso, Jwanse I. Rinpan, Mantu E. Chongs* 

*by Hisyovi Cardenas Suri, David Jimomila Bening* 

*and Benjamín Demah Nuertey*

*and Maureen O. Ekpere-Ezeugwu*

Usefulness of the Hemogram in COVID-19

COVID-19 Vaccine: A Way Out of Crisis *by Aman Sachdeva and Arup Saha*

Covid-19 Vaccines and Institutional Trust

Pharmacotherapy for COVID-19: A Ray of Hope

**Section 3**

A Review

*by John Zizzo*

*by Hemant Bherwani*


Preface

What are coronaviruses? What is SARS-CoV-2? What is its origin? Why did it suddenly appear? How does it cause disease? How do these viruses spread? How can the surrounding environment be decontaminated? How does our body

How can we diagnose these infections? What are the different diagnostic modalities?

What are the proposed treatment options? When do we treat and who do we treat?

Why are there so many vaccine candidates? Why is there reluctance and hesitancy

What is meant by a "one-health approach" and how does it affect human health?

The first section deals with the coronavirus, highlighting its properties and the demographic features of the pandemic. Additionally, it examines how we can target the virus through our immune systems in vivo and through methods of decontamination in vitro.

The second section talks about the different manifestations of the disease in various clinical cohorts including pregnant females, diabetics, and persons with cardiovascular morbidities. It examines the effect of the coronavirus on the nervous system, senses of taste and smell, and mental health. The chapter highlights the association of the virus with multiorgan dysfunction and catastrophic antiphospholipid antibody syndrome.

The third section discusses the role of the medical laboratory in diagnosis, and evaluates diagnostic methods such as the hemogram. Prevention relies on vaccines in addition to precautionary measures against exposure, yet many myths are barriers to vaccination efforts. A decline in institutional trust serves to perpetuate myths and vaccine hesitancy. As such, this section also outlines the role of pharmacotherapeutics and discusses options for home care, with an introduction to the possible role of the

The book represents the current situation. As time goes on and the situation changes

**Manal Mohammad Baddour**

Medical Microbiology and Immunology Department,

Faculty of Medicine,

Alexandria University, Alexandria, Egypt

and evolves, some of the information presented herein may become obsolete.

"one-health approach" in tackling such situations.

Over three sections, this book, *Fighting the COVID-19 Pandemic*, tackles these

to vaccination efforts? What are the myths and barriers to vaccines?

respond and fight back? Who gets complications and why?

questions and more.
