**4.2 Hypertension**

Treatment with angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARBs) could increase the expression of ACE2 and accelerate entry of the virus into the cells. However, in COVID-19 infection, impairment of the ACE2/Mas receptor pathway and increase in angiotensin-2 activity could occur, and RAAS blockade may protect against this serious lung injury. Thus it is recommended that ACEI and ARBs should continue [15].
