**2.6 High-density lipoprotein cholesterol (HDL-C)**

HDL-C increased following consumption of linoleic acid compared to stearic acid [56]. In contrast, intakes of linoleic acid decreased HDL-C compared to EPA and DHA [61] or palmitic acid [57]. However, most studies noticed no significant differences regarding HDL-C concentrations after consuming low and high amounts of linoleic acid [54, 60, 62, 64], and linoleic acid compared to oleic acid [58, 65, 66], alpha-linolenic acid [60, 63], or stearic acid [66]. Interestingly, intakes of SFAs or linoleic acid (both diets supplemented with EPA and DHA) displayed no significant differences in HDL-C concentrations [67].
